Utility of low-cost, miniaturized peristaltic and Venturi pumps in droplet microfluidics.

ABSTRACT: Many laboratory applications utilizing droplet microfluidics rely on precision syringe pumps for flow generation. In this study, the use of an open-source peristaltic pump primarily composed of 3D printed parts and a low-cost commercial Venturi pump are explored for their use as an alternative to syringe pumps for droplet microfluidics. Both devices provided stable flow (<2% RSD) over a range of 1-7 μL/min and high reproducibility in signal intensity at a droplet generation rate around 0.25 Hz (<3% RSD), which are comparable in performance to similar measurements on standard syringe pumps. As a novel flow generation source for microfluidic applications, the use of the miniaturized Venturi pump was also applied to droplet signal monitoring studies used to measure changes in concentration ov

SUBMITTER: Davis JJ 

PROVIDER: S-EPMC7897340 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature