Perianal fistulodesis - A pilot study of a novel minimally invasive surgical and medical approach for closure of perianal fistulae.

ABSTRACT:

Background

Perianal fistulae strongly impact on quality of life of affected patients.

Aim

To challenge and novel minimally invasive treatment options are needed.

Methods

Patients with Crohn's disease (CD) in remission and patients without inflammatory bowel disease (non-IBD patients) were treated with fistulodesis, a method including curettage of fistula tract, flushing with acetylcysteine and doxycycline, Z-suture of the inner fistula opening, fibrin glue instillation, and Z-suture of the outer fistula opening followed by post-operative antibiotic prophylaxis with ciprofloxacin and metronidazole for two weeks. Patients with a maximum of 2 fistula openings and no clinical or endosonographic signs of a complicated fistula were included. The primary end point was fistul

SUBMITTER: Villiger R 

PROVIDER: S-EPMC7898183 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature