Temporal dynamics of peripheral neutrophil and lymphocytes following acute ischemic stroke.

ABSTRACT:

Background

The immune response to acute ischemic stroke (AIS) is implicated in diagnosis, prognosis, and intervention; however, the temporal dynamics of leukocytes following AIS are poorly understood. The purpose of this study was to characterize peripheral leukocyte dynamics following AIS among individuals with poor and favorable outcomes.

Methods

A retrospective chart review was conducted among patients with a diagnosis of AIS who were treated at a comprehensive stroke center across a 3-year timeframe. Groups were defined according to stroke outcomes. Patients with poor outcomes were distinguished from those with favorable outcomes by discharge National Institute of Health Stroke Score, infarct size, and Modified Rankin Scale. Leukocyte counts were compared among controls

SUBMITTER: Petrone AB 

PROVIDER: S-EPMC7898194 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature