Mimicking Photosystem I with a Transmembrane Light Harvester and Energy Transfer-Induced Photoreduction in Phospholipid Bilayers.

ABSTRACT: Photosystem I (PS I) is a transmembrane protein that assembles perpendicular to the membrane, and performs light harvesting, energy transfer, and electron transfer to a final, water-soluble electron acceptor. We present here a supramolecular model of it formed by a bicationic oligofluorene 1²⁺ bound to the bisanionic photoredox catalyst eosin Y (EY^2- ) in phospholipid bilayers. According to confocal microscopy, molecular modeling, and time dependent density functional theory calculations, 1²⁺ prefers to align perpendicularly to the lipid bilayer. In presence of EY^2- , a strong complex is formed (K_a =2.1±0.1×10⁶  m^-1 ), which upon excitation of 1²⁺ leads to efficient energy transfer to EY^2- .

SUBMITTER: Pannwitz A 

PROVIDER: S-EPMC7898337 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature