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Vitamin D status and blood pressure in children and adolescents: a systematic review of observational studies.


ABSTRACT:

Background

Childhood hypertension is a growing public health problem. Simultaneously, hypovitaminosis D is widespread in this population and could be associated with hypertension. This study systematically reviewed the literature on the relationship between vitamin D status and blood pressure (BP) in children and adolescents.

Methods

Following the PRISMA guidelines, PUBMED, MEDLINE, CINAHL, EMBASE, Cochrane Library, and ClinicalTrials.gov and the gray literature without language or time restrictions were searched. We included observational studies, assessed their risk of bias, and extracted data on population characteristics, vitamin D status and BP measurements, and the association between the two variables. A narrative analysis of the studies was performed.

Results

SUBMITTER: Abboud M 

PROVIDER: S-EPMC7898425 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature