Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn's disease.

ABSTRACT:

Background

Positive effects of hyperbaric oxygen on perianal fistulas in Crohn's disease have been reported.

Aim

To assess efficacy, safety and feasibility of hyperbaric oxygen in Crohn's disease patients with therapy-refractory perianal fistulas.

Methods

Twenty consecutive patients were recruited at the out-patient fistula clinic of the Amsterdam UMC. Crohn's disease patients with high perianal fistula(s) failing conventional treatment for over 6 months were included. Exclusion criteria were presence of a stoma, rectovaginal fistula(s) and recent changes in treatment regimens. Patients received treatment with 40 hyperbaric oxygen sessions and outcome parameters were assessed at Week 16.

Results

Seven women and 13 men were included (median age 34 years). At Wee

SUBMITTER: Lansdorp CA 

PROVIDER: S-EPMC7898636 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature