A rare cause of culture negative bioprosthetic valve endocarditis: a case report of Aggregatibacter aphrophilus infection.

ABSTRACT:

Background

The prevalence of culture negative infective endocarditis (IEC) is reported as 2-7% though this figure may be as high as 70% in developing countries.¹ This higher rate will, at least in part, be due to reduced diagnostic facilities though some data suggests higher rates even when appropriate cultures were taken. The frequency is significantly elevated in patients who have already been exposed to antibiotics prior to blood cultures.^{1 , 2} A rare cause of culture negative IEC is the HACEK group of organisms that are normal habitants of the oropharyngeal flora and account for 1-3% of native valve endocarditis.³ Aggregatibacter aphrophilus (A. aphrophilus) is a member of the HACEK group of organisms.

Case summar

SUBMITTER: Wassef N 

PROVIDER: S-EPMC7898661 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature