Effects of moderate sleep restriction during 8-week calorie restriction on lipoprotein particles and glucose metabolism.

ABSTRACT:

Study objectives

This study examined how glucose, glucose regulatory hormones, insulin sensitivity, and lipoprotein subclass particle concentrations and sizes change with sleep restriction during weight loss elicited by calorie restriction.

Methods

Overweight or obese adults were randomized into an 8-week calorie restriction intervention alone (CR, n = 12; 75% female; body mass index = 31.4 ± 2.9 kg/m²) or combined with sleep restriction (CR+SR, n = 16; 75% female; body mass index = 34.5 ± 3.1 kg/m²). Participants in both groups were given the same instructions to reduce calorie intake. Those in the CR+SR group were instructed to reduce their habitual time-in-bed by 30-90 minutes 5 days each week with 2 ad libitum sleep days. Fasting venou

SUBMITTER: Sparks JR 

PROVIDER: S-EPMC7898726 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature