MAIP: a web service for predicting blood-stage malaria inhibitors.

ABSTRACT: Malaria is a disease affecting hundreds of millions of people across the world, mainly in developing countries and especially in sub-Saharan Africa. It is the cause of hundreds of thousands of deaths each year and there is an ever-present need to identify and develop effective new therapies to tackle the disease and overcome increasing drug resistance. Here, we extend a previous study in which a number of partners collaborated to develop a consensus in silico model that can be used to identify novel molecules that may have antimalarial properties. The performance of machine learning methods generally improves with the number of data points available for training. One practical challenge in building large training sets is that the data are often proprietary and cannot be straightforwardly i

SUBMITTER: Bosc N 

PROVIDER: S-EPMC7898753 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature