A gene co-association network regulating gut microbial communities in a Duroc pig population.

ABSTRACT:

Background

Analyses of gut microbiome composition in livestock species have shown its potential to contribute to the regulation of complex phenotypes. However, little is known about the host genetic control over the gut microbial communities. In pigs, previous studies are based on classical "single-gene-single-trait" approaches and have evaluated the role of host genome controlling gut prokaryote and eukaryote communities separately.

Results

In order to determine the ability of the host genome to control the diversity and composition of microbial communities in healthy pigs, we undertook genome-wide association studies (GWAS) for 39 microbial phenotypes that included 2 diversity indexes, and the relative abundance of 31 bacterial and six commensal protist genera in 390 pigs

SUBMITTER: Reverter A 

PROVIDER: S-EPMC7898758 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature