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The Effectiveness and Safety of Intravenous Dexmedetomidine of Different Concentrations Combined with Butorphanol for Post-Caesarean Section Analgesia: A Randomized Controlled Trial.


ABSTRACT:

Purpose

The present study aimed to determine the effectiveness of intravenous dexmedetomidine of different concentrations and to evaluate its maternal and neonatal safety when combined with butorphanol in parturients undergoing cesarean section.

Patients and methods

A total of 114 parturients between 24 and 43 years of age, with singleton pregnancy who underwent elective cesarean section under epidural anesthesia, were randomly allocated to four groups: group C received 0.9% sodium chloride after delivery, followed by butorphanol (3 μg·kg-1·h-1); patients in groups D1, D2, and D3 received 0.5 μg·kg-1·h-1 dexmedetomidine after delivery, followed by butorphanol (3 μg·kg-1·h-1) combined with dexmedetomidine 0.03,

SUBMITTER: Liu S 

PROVIDER: S-EPMC7899314 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature