Circulating microparticles and activated platelets as novel prognostic biomarkers in COVID-19; relation to cancer.

ABSTRACT:

Background and aim

The study aimed to determine whether the MPs levels and platelet activation are affected by the COVID-19 infection in both malignant and non-malignant patients compared to healthy individuals and define their contribution to the COVID-19 associated coagulopathy and the relation of these MPs to other hematologic parameters.

Patients and methods

We recruited 23 malignant patients with reverse transcription polymerase chain reaction (RT-PCR) positive COVID-19, also, 19 COVID-19 non-malignant patients, and 20 healthy volunteers were also enrolled for comparison. Blood samples were collected from patients and healthy donors into 5 mL vacutainer tube containing 3.5% buffered sodium citrate solution for measurement of total microparticles (TMPs), platelet micropa

SUBMITTER: Zahran AM 

PROVIDER: S-EPMC7899358 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature