Features of the gut microbiota in ulcerative colitis patients with depression: A pilot study.

ABSTRACT:

Abstract

Despite the establishment of the links between ulcerative colitis (UC) and depression, between UC and gut microbiota, few correlations between depression and gut microbiota have yet been demonstrated especially in ulcerative colitis patients. The objective of our study was therefore to determine whether the comorbidity of depressive disorder in ulcerative colitis patients correlate with alterations in the gut microbiota and to identify the specific microbiota signatures associated with depression.Between March 2017 and February 2018, 31 healthy volunteers, 31 UC patients without depression, and 31 UC patients with depression from Longhua Hospital were enrolled. Clinical data and fecal samples were collected for each patient. Fecal bacteria were identified using 16 s rRNA s

SUBMITTER: Chen DL 

PROVIDER: S-EPMC7899815 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature