Predictors of Metachronous Risk Polyps After Index Colonoscopy.

ABSTRACT:

Introduction

Guidelines for surveillance after polypectomy are lacking in strong evidence. Our aim was to identify some precursors of colorectal cancer lesions at 3 years after polypectomy to improve stratification and surveillance programs.

Methods

We included patients with high-risk lesions (HRLs), defined as advanced adenoma (AA), large serrated polyps (SPs), and multiplicity (≥3 of any adenomas/SPs). Data on age, sex, cardiovascular risk factors, pharmacological treatment, and the histological characteristics in each individual, and mutations in genes involved in the most advanced index polyp, were collected. Parameters independently associated with a metachronous HRL diagnosis were evaluated through univariate and multivariate analyses. The results are reported as odds

SUBMITTER: Carot L 

PROVIDER: S-EPMC7899856 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature