Effect of Time to Surgery of Colorectal Liver Metastases on Survival.

ABSTRACT:

Purpose

Resection of liver-only colorectal liver metastases (CRLM) with perioperative chemotherapy is potentially curative. Specific primary tumor and liver metastasis characteristics have been validated to estimate the risk of recurrence. We hypothesize that the time interval from diagnosis of CRLM to surgery, or time to surgery (TTS), is clinically prognostic.

Methods

Patients from a prospectively maintained institutional database at a Comprehensive Cancer Center from May 2003 to January 2018 were reviewed. Clinicopathologic, perioperative treatment, and TTS data were collected. TTS was categorized into short (< 3 months), intermediate (3-6 months), and long (> 6 months) intervals.

Results

Two hundred eighty-one patients were identified. While overall survival (OS)

SUBMITTER: Chen EY 

PROVIDER: S-EPMC7900034 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature