Foveal Differentiation and Inner Retinal Displacement Are Arrested in Extremely Premature Infants.

ABSTRACT:

Purpose

Children with a history of prematurity often have poorly developed foveae but when during development foveal differences arise. We hypothesize that the course of foveal development is altered from the time of preterm birth.

Methods

Eyes of 102 preterm infants undergoing retinopathy of prematurity screening examinations in the STudy of Eye imaging in Premature infantS (BabySTEPS) (NCT02887157) were serially imaged between 30 and 42 weeks postmenstrual age (PMA) using handheld optical coherence tomography systems. Total retinal thickness, inner retinal layer (IRL) thickness, and outer retinal layer (ORL) thickness were measured at the foveal center and parafovea. Foveal put depth, IRL thickness, and ORL thickness were compared between infants born at different gestatio

SUBMITTER: O'Sullivan ML 

PROVIDER: S-EPMC7900865 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature