Early Astigmatism Can Alter Myopia Development in Chickens.

ABSTRACT:

Purpose

To determine the effects of optically imposed astigmatism on myopia development in chickens.

Methods

Chicks were randomly assigned to wear either spherical (-10D, "LIM", n = 14) or sphero-cylindrical lenses (n ≥ 19 in each group) monocularly for a week from 5 days of age. All lenses imposed the same magnitude of spherical-equivalent hyperopic defocus (-10D), with the two astigmatic magnitudes (-8D or -4D) and four axes (45°, 90°, 135°, or 180°) altered to simulate four subtypes of clinical astigmatism. At the end of the treatment, refractive state was measured for all birds, whereas ocular axial dimensions and corneal curvature were measured for subsets of birds.

Results

Sphero-cylindrical lens wear produced significant impacts on nearly all refractive paramet

SUBMITTER: Vyas SA 

PROVIDER: S-EPMC7900885 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature