Dataset Information

Large-Scale Centrifugal Multispinning Production of Polymer Micro- and Nanofibers for Mask Filter Application with a Potential of Cospinning Mixed Multicomponent Fibers.

ABSTRACT: Recently, the polymer nanofiber web is in high demand as a strong barrier against harmful particles due to its high capture efficiency and strong droplet-blocking ability. As an advanced spinning technique, the centrifugal multispinning system was designed by sectioning a rotating disk into triple subdisks, showing mass producibility of polymer nanofibers with cospinning ability. Using the system, gram-scale production of polystyrene (PS), poly(methyl methacrylate), and polyvinylpyrrolidone (PVP) was demonstrated, showing a possibility for versatile use of the system. Moreover, a high production rate of ∼25 g/h for PS nanofibers was achieved, which is ∼300× higher than that of the usual electrospinning process. Utilizing the cospinning ability, we controlled the contact angle and electrostatic charge of the multicomponent nanofiber web by adjusting the relative amounts of PS and PVP fibers, showing a potential for functional textile application. With the fabricated PS nanofiber-based filters, we achieved high capture efficiency up to ∼97% with outstanding droplet-blocking ability.

SUBMITTER: Kwak BE

PROVIDER: S-EPMC7901235 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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Large-Scale Centrifugal Multispinning Production of Polymer Micro- and Nanofibers for Mask Filter Application with a Potential of Cospinning Mixed Multicomponent Fibers.

Kwak Byeong Eun BE Yoo Hyo Jeong HJ Lee Eungjun E Kim Do Hyun DH

ACS macro letters 20210217

Recently, the polymer nanofiber web is in high demand as a strong barrier against harmful particles due to its high capture efficiency and strong droplet-blocking ability. As an advanced spinning technique, the centrifugal multispinning system was designed by sectioning a rotating disk into triple subdisks, showing mass producibility of polymer nanofibers with cospinning ability. Using the system, gram-scale production of polystyrene (PS), poly(methyl methacrylate), and polyvinylpyrrolidone (PVP ...[more]

PMID: 34192093

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Project description:The worldwide COVID-19 pandemic has led to an attention on the usage of personal protective face masks. However, the longevity and safety of the commercial face masks are limited due to the charge dissipation of the electret meltblown nonwovens, which are dominate in the face mask filters. Herein, we design a type of multi-layer structured nonwovens using meltblowing and electrospinning technologies. The complex nonwovens involving meltblown and electrospun fibers are designed to possess multilevel fiber diameters and pore sizes. The micro/nanofibers with porous and wrinkled surface morphologies can well capture particulate matters (PMs), and the multilevel pore sizes contribute to low air resistance under high filtration efficiency. Airflow field simulation was carried out to understand the pressure distribution within the nonwovens in the filtration process. Meanwhile, by adding Ag nanoparticles (AgNPs) as additives, the nonwovens exhibit excellent antibacterial performance. The resultant nonwovens exhibit filtration efficiency of 99.1% for PM0.3 and low pressure drop of 105 Pa under the 10.67 cm/s inlet air velocity, and antibacterial rate of > 99.99% for Escherichia coli. These performances and functions make the designed complex nonwovens a promising filter core for face masks.Electronic supplementary materialSupplementary material (Fig. S1. The filtration efficiencies of a brand of surgical mask changes with the storage time under the condition of 100% humidity. Fig. S2. The FE-SEM images of the fibers after blocking PMs. Fig. S3. Illustration of 3D structure models of the nonwovens. Fig. S4. Diameter distribution of AgNPs. Table S1. The structure parameters and filtration performances of the PP-M fibers with and without pores and wrinkles. Table S2. Filtration performance of PP-M/PLA-M/PLA-N nonwovens and commercial face masks. Table S3. The structural parameters for the nonwovens. Table S4. The filtration efficiencies and pressure drops of the PP, PE spunbonded nonwovens, and PP-M/PLA-M/PLA-N@AgNPs nonwovens) is available in the online version of this article at 10.1007/s12274-022-4350-2.

Project description:BackgroundThe success of forensic DNA analysis is limited by the size, quality and purity of biological evidence found at crime scenes. Sample impurities can inhibit PCR, resulting in partial or negative DNA profiles. Various DNA purification methods are applied to remove impurities, for example, employing centrifugal filter devices. However, irrespective of method, DNA purification leads to DNA loss. Here we evaluate the filter devices Amicon Ultra 30 K and Microsep 30 K with respect to recovery rate and general performance for various types of PCR-inhibitory crime scene samples.MethodsRecovery rates for DNA purification using Amicon Ultra 30 K and Microsep 30 K were gathered using quantitative PCR. Mock crime scene DNA extracts were analyzed using quantitative PCR and short tandem repeat (STR) profiling to test the general performance and inhibitor-removal properties of the two filter devices. Additionally, the outcome of long-term routine casework DNA analysis applying each of the devices was evaluated.ResultsApplying Microsep 30 K, 14 to 32% of the input DNA was recovered, whereas Amicon Ultra 30 K retained 62 to 70% of the DNA. The improved purity following filter purification counteracted some of this DNA loss, leading to slightly increased electropherogram peak heights for blood on denim (Amicon Ultra 30 K and Microsep 30 K) and saliva on envelope (Amicon Ultra 30 K). Comparing Amicon Ultra 30 K and Microsep 30 K for purification of DNA extracts from mock crime scene samples, the former generated significantly higher peak heights for rape case samples (P-values <0.01) and for hairs (P-values <0.036). In long-term routine use of the two filter devices, DNA extracts purified with Amicon Ultra 30 K were considerably less PCR-inhibitory in Quantifiler Human qPCR analysis compared to Microsep 30 K.ConclusionsAmicon Ultra 30 K performed better than Microsep 30 K due to higher DNA recovery and more efficient removal of PCR-inhibitory substances. The different performances of the filter devices are likely caused by the quality of the filters and plastic wares, for example, their DNA binding properties. DNA purification using centrifugal filter devices can be necessary for successful DNA profiling of impure crime scene samples and for consistency between different PCR-based analysis systems, such as quantification and STR analysis. In order to maximize the possibility to obtain complete STR DNA profiles and to create an efficient workflow, the level of DNA purification applied should be correlated to the inhibitor-tolerance of the STR analysis system used.

Dataset Information

Large-Scale Centrifugal Multispinning Production of Polymer Micro- and Nanofibers for Mask Filter Application with a Potential of Cospinning Mixed Multicomponent Fibers.

Publications

Large-Scale Centrifugal Multispinning Production of Polymer Micro- and Nanofibers for Mask Filter Application with a Potential of Cospinning Mixed Multicomponent Fibers.

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