Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test.

ABSTRACT:

Background

Sensitive and high throughput molecular detection assays are essential during the coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The vast majority of the SARS-CoV-2 molecular assays use nasopharyngeal swab (NPS) or oropharyngeal swab (OPS) specimens collected from suspected individuals. However, using NPS or OPS as specimens has apparent drawbacks, e.g. the collection procedures for NPS or OPS specimens can be uncomfortable to some people and may cause sneezing and coughing which in turn generate droplets and/or aerosol particles that are of risk to healthcare workers, requiring heavy use of personal protective equipment. There have been recent studies indicating that self-collected saliva specime

SUBMITTER: Sun Q 

PROVIDER: S-EPMC7901781 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature