Examination of the Prefrontal Cortex Hemodynamic Responses to the Fist-Edge-Palm Task in Naive Subjects Using Functional Near-Infrared Spectroscopy.

ABSTRACT: The Fist-Edge-Palm (FEP) task, a manual hand task, has been used to detect frontal dysfunctions in clinical situations: its performance failures are observed in various prefrontal cortex (PFC)-related disorders, including schizophrenia. However, previous imaging studies reported that the performance of the FEP task activated motor-related areas, but not the PFC. Here, we aimed to investigate the relationships between the performance of the FEP task and PFC functions. Hemodynamic activity in the PFC, including the dorsolateral PFC (area 46) and frontal pole (area 10), was recorded. Healthy young subjects performed the FEP task as well as a palm tapping (PT) task (control task) three times. The subjects also completed a Wisconsin Card Sorting Test (WCST) and Schizotypal Personality Scale (ST

SUBMITTER: Kobayashi S 

PROVIDER: S-EPMC7901956 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature