Effects of bilingualism on age at onset in two clinical Alzheimer's disease variants.

ABSTRACT:

Introduction

The effect of bilingualism on age at onset has yet to be examined within different clinical variants of Alzheimer's disease.

Methods

We reviewed the research charts of 287 well-characterized participants with either amnestic Alzheimer's dementia or logopenic variant primary progressive aphasia (lvPPA) and identified bilingual speakers based on regular use of two or more languages and/or ability to communicate with native speakers in two or more languages. We evaluated whether bilingual speakers demonstrated a delay in age of symptom onset relative to monolingual speakers while controlling for other variables known to influence cognitive reserve.

Results

A 5-year delay in age at symptom onset was observed for bilingual relative to monolingual speakers with

SUBMITTER: de Leon J 

PROVIDER: S-EPMC7902304 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature