High frequency percussive ventilation in pediatric acute respiratory failure.

ABSTRACT:

Objective

High frequency percussive ventilation (HFPV) is used in acute respiratory failure, but is poorly described in pediatrics. We aimed to describe the clinical characteristics, ventilator settings, and outcomes of a large pediatric cohort, and to determine predictors of who would benefit from HFPV.

Hypothesis

Gas exchange 2 h after HFPV initiation predicts success.

Design

Single center retrospective cohort study testing association between gas exchange 2 h after HFPV initiation with success, defined a priori.

Patients

Intubated children on HFPV for ≥2 h from 2012 to 2018.

Methods

We described indications, ventilator settings, and gas exchange immediately before, 2 h after, and at termination of HFPV. Univariate and multivariate regression tested as

SUBMITTER: Butler AD 

PROVIDER: S-EPMC7902396 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature