Larger increase in trait negative affect is associated with greater future cognitive decline and vice versa across 23 years.

ABSTRACT:

Background

Trait negative affect (NA) is a central feature of anxiety and depression disorders. Neurocognitive and scar models propose that within-person increase in NA across one period of time relates to a decline in cognitive functioning at a future period of time and vice versa. Yet, there has been little research on whether a within-person change in trait NA across one time-lag precedes and is associated with a change in cognition across a future time lag and vice versa. Due to a growing aging population, such knowledge can inform evidence-based prevention.

Methods

Participants were 520 dementia-free community-dwelling adults (mean age = 59.76 years [standard deviation = 8.96], 58.08% females). Trait-level NA (negative emotionality scale), spatial cognition (block desig

SUBMITTER: Zainal NH 

PROVIDER: S-EPMC7902413 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature