Staphylococcus aureus ST59: Concurrent but Separate Evolution of North American and East Asian Lineages.

ABSTRACT: Despite initially being described in North America, Staphylococcus aureus (SA) sequence type ST59 is the most commonly isolated sequence type in Eastern Asia. The origins and evolution of this strain type remains unclear and therefore we gathered a collection of ST59 isolates from Canada and mainland China for a detailed genetic analysis of the lineage. Bayesian inference phylogenomic analysis of our isolates, along with previously published ST59 sequences indicated that the lineage could be divided into 6 distinct subgroups (WGS-1 thorough 6), each having distinct molecular characteristics. Analysis also demonstrated the concurrent but separate evolution of North American and East Asian lineages, as well as the extensive diversification of the East Asian lineage. The presence of a

SUBMITTER: McClure JA 

PROVIDER: S-EPMC7902796 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature