Prophylactic cranial irradiation in patients with small cell lung cancer in The Netherlands: A population-based study.

ABSTRACT:

Introduction

Controversy has arisen regarding the benefit of prophylactic cranial irradiation (PCI) in patients with small cell lung cancer (SCLC), particularly since the 2017 Takahashi trial publication that supports MRI surveillance in extensive-stage (ES-)SCLC. The primary aim of this study was to assess trends and determinants in PCI use over the years 2010-2018. A secondary aim was to determine contemporary practice considerations among radiation oncologists (ROs).

Methods

A nationwide population-based cohort study was conducted using the Netherlands Cancer Registry data on all newly diagnosed SCLC patients (2010-2018). The change in PCI frequency over the years and determinants for PCI were analyzed using logistic regression models. Second, an online survey was perform

SUBMITTER: Tomassen ML 

PROVIDER: S-EPMC7903055 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature