Does cranberry extract reduce antibiotic use for symptoms of acute uncomplicated urinary tract infections (CUTI)? A feasibility randomised trial.

ABSTRACT:

Objectives

To determine the feasibility of conducting a randomised trial of the effectiveness of cranberry extract in reducing antibiotic use by women with symptoms of acute, uncomplicated urinary tract infection (UTI).

Design

Open-label feasibility randomised parallel group trial.

Setting

Four general practices in Oxfordshire.

Participants

Women aged 18 years and above presenting to general practice with symptoms of acute, uncomplicated UTI.

Interventions

Women were randomly assigned using Research Electronic Data Capture in a 1:1:1 ratio to: (1) immediate antibiotics alone (n=15); (2) immediate antibiotics and immediate cranberry capsules for up to 7 days (n=15); or (3) immediate cranberry capsules and delayed antibiotics for self-initiation in case of

SUBMITTER: Gbinigie O 

PROVIDER: S-EPMC7903114 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature