Persistent organic pollutants and couple fecundability: a systematic review.

ABSTRACT:

Background

Despite increasing regulation, exposure to persistent organic pollutants (POPs) remains a serious public health concern due to their accumulation in the environment and ability to biomagnify up the food chain. POPs are associated with endocrine-disrupting effects including adverse reproductive outcomes that could affect fecundability, i.e. the capacity to conceive a pregnancy, quantified as time to pregnancy (TTP).

Objective and rationale

Results of epidemiologic studies that examine the impact of various chemical classes of POPs on TTP have not been synthesised. We undertook a systematic review to summarise the strength of evidence for associations of four common groups of POPs with couple fecundability and to identify gaps and limitations in the literature in or

SUBMITTER: Kahn LG 

PROVIDER: S-EPMC7903116 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature