A Contemporary Report of Clinical Outcomes in Patients with Melanoma Brain Metastases.

ABSTRACT: Background: Brain metastases are observed in more than 40% of all patients with stage 4 melanoma. In recent years, more extensive use of stereotactic radiation (STRT) and the advent of immune checkpoint inhibitors have positively impacted outcomes in patients with metastatic melanoma.brain metastases. Here, we examined real world clinical outcomes of patients presenting with melanoma brain metastases (MBMs). Methods: This retrospective review evaluated MBMs patients treated at The Ottawa Hospital from April 2000 to July 2017. Clinical, radiologic, pathologic and treatment information were gathered from the electronic medical records. The primary outcome was overall survival. The proportional Cox regression model was employed for survival data, while the Fisher's exact and Man

SUBMITTER: Phillips WJ 

PROVIDER: S-EPMC7903273 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature