Lack of association between polymorphism of IL-2 -330T/G and pulmonary tuberculosis among Caucasians.

ABSTRACT: This meta-analysis was conducted to assess the consistency and strength of the relationship between polymorphism of IL-2 -330T/G and susceptibility to pulmonary tuberculosis (TB). PubMed, Web of Knowledge and CNKI were searched to find eligible studies about the relationship between IL-2 -330T/G polymorphism and susceptibility to pulmonary TB. A total of eight studies comprising 971 cases and 1519 controls were grouped together for the purpose of elucidating the relationship between polymorphism of IL-2 -330T/G and pulmonary TB susceptibility. The allele model (G vs. T: odds ratio (OR) = 1.34; 95% confidence interval (CI) 1.05-1.71, P_het = 0.001) and the recessive model (GG+GT vs. TT: OR = 1.60; 95% CI 1.08-2.38, P_het = 0.0001) showed an increased risk o

SUBMITTER: Ge H 

PROVIDER: S-EPMC7903529 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature