Lung diffusing capacity for nitric oxide and carbon monoxide following mild-to-severe COVID-19.

ABSTRACT: A decreased lung diffusing capacity for carbon monoxide (DL_CO ) has been reported in a variable proportion of subjects over the first 3 months of recovery from severe coronavirus disease 2019 (COVID-19). In this study, we investigated whether measurement of lung diffusing capacity for nitric oxide (DL_NO ) offers additional insights on the presence and mechanisms of gas transport abnormalities. In 94 subjects, recovering from mild-to-severe COVID-19 pneumonia, we measured DL_NO and DL_CO between 10 and 266 days after each patient was tested negative for severe acute respiratory syndrome coronavirus 2. In 38 subjects, a chest computed tomography (CT) was available for semiquantitative analysis at six axial levels and automatic quantitative analysis o

SUBMITTER: Barisione G 

PROVIDER: S-EPMC7903940 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature