The Role of Probiotics, Prebiotics and Synbiotics in Combating Multidrug-Resistant Organisms.

ABSTRACT: The prevalence of multidrug-resistant organisms is increasing worldwide, posing a unique challenge to global health care systems. Novel approaches are needed to combat the spread of infection with these organisms. The enteric microbiome, and in particular the resistome, offers a unique target in both the prevention of infection with these organisms and the acquisition and spread within the community. We highlight a novel approach to combat multidrug-resistant organisms: the use of prebiotics, probiotics, and synbiotics to manipulate the microbiome and resistome. This review summarizes the published literature and clinical trials related to these products to date, with a focus on efficacious trials. It highlights the probable mechanism of action for each product, as well as its safety profi

SUBMITTER: Newman AM 

PROVIDER: S-EPMC7904027 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature