Fast T₁ measurement of cortical bone using 3D UTE actual flip angle imaging and single-TR acquisition (3D UTE-AFI-STR).

ABSTRACT:

Purpose

To describe a new method for accurate T₁ measurement of cortical bone that fits the data sets of both 3D UTE actual flip angle imaging (UTE-AFI) and UTE with a single TR (UTE-STR) simultaneously (UTE-AFI-STR).

Theory and methods

To make both the constant values and longitudinal mapping functions in the signal equations for UTE-AFI and UTE-STR identical, the same RF pulses and flip angles were used. Therefore, there were three unknowns in the three equations. This was sufficient to fit the data. Numerical simulation as well as ex vivo and in vivo cortical bone studies were performed to validate the T₁ measurement accuracy with the UTE-AFI-STR method. The original UTE-AFI variable TR (VTR) (ie, combined UTE-AFI and UTE with VTR) and simultaneous f

SUBMITTER: Wei Z 

PROVIDER: S-EPMC7904585 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature