Reirradiation practices for children with diffuse intrinsic pontine glioma.

ABSTRACT:

Background

Diffuse intrinsic pontine gliomas (DIPGs) are a leading cause of brain tumor deaths in children. Current standard of care includes focal radiation therapy (RT). Despite clinical improvement in most patients, the effect is temporary and median survival is less than 1 year. The use and benefit of reirradiation have been reported in progressive DIPG, yet standardized approaches are lacking. We conducted a survey to assess reirradiation practices for DIPG in North America.

Methods

A 14-question REDCap survey was disseminated to 396 North American physicians who care for children with CNS tumors.

Results

The response rate was 35%. Participants included radiation-oncologists (63%; 85/135) and pediatric oncologists/neuro-oncologists (37%; 50/135). Most physicians

SUBMITTER: Cacciotti C 

PROVIDER: S-EPMC7906270 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature