Mathematical modelling of post-filter ionized calcium during citrate anticoagulated continuous renal replacement therapy.

ABSTRACT:

Background/aims

Post-filter ionized calcium (iCa) measured on a blood gas analyzer (BGA) during regional citrate anticoagulated continuous renal replacement therapy (CRRT) are needed to control the regime. This increases the workload and requires attention including interpretation of blood analyses. Two algorithms were developed to calculate the post-filter iCa instead. The first algorithm used measured systemic total calcium and the second used a selected set of values from an initial blood gas sample as input.

Methods

Calculated post-filter iCa values were compared to real blood gas analyses. 57 patients treated at the intensive care unit at Skåne University Hospital in Lund during 2010-2017 were included after applying inclusion and exclusion criteria. Clinical and machin

SUBMITTER: Forsal I 

PROVIDER: S-EPMC7906315 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature