Computational fluid dynamics of the right atrium: Assessment of modelling criteria for the evaluation of dialysis catheters.

ABSTRACT: Central venous catheters are widely used in haemodialysis therapy, having to respect design requirements for appropriate performance. These are placed within the right atrium (RA); however, there is no prior computational study assessing different catheter designs while mimicking their native environment. Here, a computational fluid dynamics model of the RA, based on realistic geometry and transient physiological boundary conditions, was developed and validated. Symmetric, split and step catheter designs were virtually placed in the RA and their performance was evaluated by: assessing their interaction with the RA haemodynamic environment through prediction of flow vorticity and wall shear stress (WSS) magnitudes (1); and quantifying recirculation and tip shear stress (2). Haemodynamic pre

SUBMITTER: de Oliveira DC 

PROVIDER: S-EPMC7906423 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature