Apoptosis of proximal stump postganglionic brachial plexus injury, before and after six months post-trauma.

ABSTRACT:

Background

The success of the micro-surgery procedure for the treatment of postganglionic brachial plexus injury was influenced by several factors, including the surgical timing and also the viability of the proximal stump. This study evaluates the evidence of apoptosis in the brachial plexus proximal stump and its correlation with the surgical timing.

Methods

Proximal stump biopsy of postganglionic brachial plexus injury patients were obtained during nerve procedure surgery. The samples were grouped based on the surgical timing, before six months post-trauma (early group) and after six months post-trauma (late group). The apoptosis of motorneurons was evaluated by immunohistochemistry expression of Caspase-3, TNF-α, Caspase-8, and Caspase-9.

Results

Immunohistochemis

SUBMITTER: Adyaksa G 

PROVIDER: S-EPMC7907218 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature