Sex Differences in Cognitive Decline Among US Adults.

ABSTRACT:

Importance

Sex differences in dementia risk are unclear, but some studies have found greater risk for women.

Objective

To determine associations between sex and cognitive decline in order to better understand sex differences in dementia risk.

Design, setting, and participants

This cohort study used pooled analysis of individual participant data from 5 cohort studies for years 1971 to 2017: Atherosclerosis Risk in Communities Study, Coronary Artery Risk Development in Young Adults Study, Cardiovascular Health Study, Framingham Offspring Study, and Northern Manhattan Study. Linear mixed-effects models were used to estimate changes in each continuous cognitive outcome over time by sex. Data analysis was completed from March 2019 to October 2020.

Exposure

Sex.

M

SUBMITTER: Levine DA 

PROVIDER: S-EPMC7907956 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature