Sleep disorders in rare genetic syndromes: a meta-analysis of prevalence and profile.

ABSTRACT:

Background

Sleep disorders are common in people with intellectual disability (ID) and autism, with growing evidence of diverse sleep profiles across ID associated genetic syndromes. Documenting the prevalence and profile of specific sleep disorders in syndromes will quantify syndrome-driven 'risk', inform prognosis and enhance understanding of aetiology of sleep disorders.

Method

Following PRISMA guidelines for meta-analysis, we searched Ovid PsycINFO, Ovid MEDLINE, Ovid Embase, Web of Science and PubMed Central with use of syndrome-specific keywords and 60 sleep-related search terms. We screened and extracted papers that reported sleep disorder prevalence data for five or more individuals within a genetic syndrome, and applied quality criteria to produce a quality-effects p

SUBMITTER: Agar G 

PROVIDER: S-EPMC7908701 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature