Accuracy of urine flow cytometry and urine test strip in predicting relevant bacteriuria in different patient populations.

ABSTRACT:

Background

Urinary tract infection (UTI) is diagnosed combining urinary symptoms with demonstration of urine culture growth above a given threshold. Our aim was to compare the diagnostic accuracy of Urine Flow Cytometry (UFC) with urine test strip in predicting bacterial growth and in identifying contaminated urine samples, and to derive an algorithm to identify relevant bacterial growth for clinical use.

Methods

Species identification and colony-forming unit (CFU/ml) quantification from bacterial cultures were matched to corresponding cellular (leucocytes/epithelial cells) and bacteria counts per μl. Results comprise samples analysed between 2013 and 2015 for which urine culture (reference standard) and UFC and urine test strip data (index tests, Sysmex UX-2000) were availa

SUBMITTER: Gehringer C 

PROVIDER: S-EPMC7908726 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature