Development of a model for predicting the 4-year risk of symptomatic knee osteoarthritis in China: a longitudinal cohort study.

ABSTRACT:

Objectives

We aimed to develop a model for predicting the 4-year risk of knee osteoarthritis (KOA) based on survey data obtained via a random, nationwide sample of Chinese individuals.

Methods

Data was analyzed from 8193 middle-aged and older adults included in the China Health and Retirement Longitudinal Study (CHARLS). The incident of symptomatic KOA was defined as participants who were free of symptomatic KOA at baseline (CHARLS2011) and diagnosed with symptomatic KOA at the 4-year follow-up (CHARLS2015). The effects of potential predictors on the incident of KOA were estimated using logistic regression models and the final model was internally validated using the bootstrapping technique. Model performance was assessed based on discrimination-area under the receiver opera

SUBMITTER: Wang L 

PROVIDER: S-EPMC7908741 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature