A quest to identify suitable organic tracers for estimating children's dust ingestion rates.

ABSTRACT: Chemical exposure via dust ingestion is of great interest to researchers and regulators because children are exposed to dust through their daily activities, and as a result, to the many chemicals contained within dust. Our goal was to develop a workflow to identify and rank organic chemicals that could be used as tracers to calculate children's dust ingestion rates. We proposed a set of criteria for a chemical to be considered a promising tracer. The best tracers must be (1) ubiquitous in dust, (2) unique to dust, (3) detectable as biomarkers in accessible biological samples, and (4) have available or obtainable ADME information for biomarker-based exposure reconstruction. To identify compounds meeting these four criteria, we developed a workflow that encompasses non-targeted analysis appr

SUBMITTER: Panagopoulos Abrahamsson D 

PROVIDER: S-EPMC7909007 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature