A simplified protocol for individualized regional citrate anticoagulation for hemodialysis: A single-center, randomized clinical study.

ABSTRACT:

Introduction

The lack of individualized treatment protocols and complicated procedures are important factors limiting the use of regional citrate anticoagulation (RCA) technology in hemodialysis. This study aims to validate the safety and efficacy of a simplified individualized RCA protocol for hemodialysis.

Materials and methods

From June 2019 to August 2019, 45 patients with active bleeding or bleeding tendency undergoing maintenance hemodialysis in the Nephrology Department of the First Affiliated Hospital of Nanchang University were randomly divided into a modified conventional RCA protocol group with a low-flux dialyzer, a simplified individualized RCA protocol group with a high-flux dialyzer, and a simplified individualized RCA protocol group with a low-flux dialyzer.<

SUBMITTER: Luo L 

PROVIDER: S-EPMC7909225 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature