Vaginal, Cervical and Uterine pH in Women with Normal and Abnormal Vaginal Microbiota.

ABSTRACT: Healthy women of reproductive age have a vaginal pH around 4.5, whereas little is known about pH in the upper genital tract. A shift in the vaginal microbiota may result in an elevated pH in the upper genital tract. This might contribute to decreased fertility and increased risk of preterm birth. Therefore, we aimed to measure pH in different compartments of the female genital tract in both nonpregnant and pregnant women, stratifying into a normal and abnormal vaginal microbiota. In this descriptive study, we included 6 nonpregnant, 12 early-pregnant, and 8 term-pregnant women. A pH gradient was recorded with a flexible pH probe. An abnormal vaginal microbiota was diagnosed by a quantitative polymerase chain reaction technique for Atopobiumvaginae; Sneathiasanguinegens; Leptotrichiaamnioni

SUBMITTER: Lykke MR 

PROVIDER: S-EPMC7909242 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature