Placental growth factor measurements in the assessment of women with suspected Preeclampsia: A stratified analysis of the PARROT trial.

ABSTRACT:

Objective

Placental growth factor testing decreases time to recognition of preeclampsia and may reduce severe maternal adverse outcomes. This analysis aims to describe the clinical phenotype of women by PlGF concentration, and to determine the mechanism(s) underpinning the reduction in severe maternal adverse outcomes in the PARROT trial, in order to inform how PlGF testing may be optimally used within clinical management algorithms.

Study design

This was a planned secondary analysis from the PARROT trial that compared revealed PlGF testing and management guidance with usual care in the assessment of women with suspected preterm preeclampsia.

Main outcome measures

Maternal and perinatal outcomes following stratification of women by trial group, and measured PlGF conce

SUBMITTER: Duhig KE 

PROVIDER: S-EPMC7909322 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature