Fluid-structure interactions (FSI) based study of low-density lipoproteins (LDL) uptake in the left coronary artery.

ABSTRACT: The purpose of this study is to compare the effect of the different physical factors on low-density lipoproteins (LDL) accumulation from flowing blood to the arterial wall of the left coronary arteries. The three-dimensional (3D) computational model of the left coronary arterial tree is reconstructed from a patient-specific computed tomography angiography (CTA) image. The endothelium of the coronary artery is represented by a shear stress dependent three-pore model. Fluid-structure interaction ([Formula: see text]) based numerical method is used to study the LDL transport from vascular lumen into the arterial wall. The results show that the high elastic property of the arterial wall decreases the complexity of the local flow field in the coronary bifurcation system. The places of high leve

SUBMITTER: Chen X 

PROVIDER: S-EPMC7910311 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature