Renal Dopamine Receptors and Oxidative Stress: Role in Hypertension.

ABSTRACT: Significance: The kidney plays an important role in the long-term control of blood pressure. Oxidative stress is one of the fundamental mechanisms responsible for the development of hypertension. Dopamine, via five subtypes of receptors, plays an important role in the control of blood pressure by various mechanisms, including the inhibition of oxidative stress. Recent Advances: Dopamine receptors exert their regulatory function to decrease the oxidative stress in the kidney and ultimately maintain normal sodium balance and blood pressure homeostasis. An aberration of this regulation may be involved in the pathogenesis of hypertension. Critical Issues: Our present article reviews the important role of oxidative stress and intrarenal dopaminer

SUBMITTER: Yang J 

PROVIDER: S-EPMC7910420 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature