Association between antecedent statin use and decreased mortality in hospitalized patients with COVID-19.

ABSTRACT: The coronavirus disease 2019 (COVID-19) can result in a hyperinflammatory state, leading to acute respiratory distress syndrome (ARDS), myocardial injury, and thrombotic complications, among other sequelae. Statins, which are known to have anti-inflammatory and antithrombotic properties, have been studied in the setting of other viral infections, but their benefit has not been assessed in COVID-19. This is a retrospective analysis of patients admitted with COVID-19 from February 1^st through May 12^th, 2020 with study period ending on June 11^th, 2020. Antecedent statin use was assessed using medication information available in the electronic medical record. We constructed a multivariable logistic regression model to predict the propensity of receiving statins

SUBMITTER: Gupta A 

PROVIDER: S-EPMC7910606 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature