Virus Etiology, Diversity and Clinical Characteristics in South African Children Hospitalised with Gastroenteritis.

ABSTRACT:

Background

Viral gastroenteritis remains a major cause of hospitalisation in young children. This study aimed to determine the distribution and diversity of enteric viruses in children ≤5 years, hospitalised with gastroenteritis at Kalafong Provincial Tertiary Hospital, Pretoria, South Africa, between July 2016 and December 2017.

Methods

Stool specimens (n = 205) were screened for norovirus GI and GII, rotavirus, sapovirus, astrovirus and adenovirus by multiplex RT-PCR. HIV exposure and FUT2 secretor status were evaluated. Secretor status was determined by FUT2 genotyping.

Results

At least one gastroenteritis virus was detected in 47% (96/205) of children. Rotavirus predominated (46/205), followed by norovirus (32/205), adenovirus (15/205), sapovi

SUBMITTER: Rossouw E 

PROVIDER: S-EPMC7911269 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature