Impact of Acid-Base Status on Mortality in Patients with Acute Pesticide Poisoning.

ABSTRACT: We investigated clinical impacts of various acid-base approaches (physiologic, base excess (BE)-based, and physicochemical) on mortality in patients with acute pesticide intoxication and mutual intercorrelated effects using principal component analysis (PCA). This retrospective study included patients admitted from January 2015 to December 2019 because of pesticide intoxication. We compared parameters assessing the acid-base status between two groups, survivors and non-survivors. Associations between parameters and 30-days mortality were investigated. A total of 797 patients were analyzed. In non-survivors, pH, bicarbonate concentration (HCO3-), total concentration of carbon dioxide (tCO2), BE, and effective strong ion difference (SIDe) were lower and apparent strong ion difference (SIDa),

SUBMITTER: Gil HW 

PROVIDER: S-EPMC7911411 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature