Antioxidants for the Treatment of Breast Cancer: Are We There Yet?

ABSTRACT: Breast cancer is the most frequent cancer and the leading cause of cancer death in women. Oxidative stress and the generation of reactive oxygen species (ROS) have been related to cancer progression. Compared to their normal counterparts, tumor cells show higher ROS levels and tight regulation of REDOX homeostasis to maintain a low degree of oxidative stress. Traditionally antioxidants have been extensively investigated to counteract breast carcinogenesis and tumor progression as chemopreventive agents; however, there is growing evidence indicating their potential as adjuvants for the treatment of breast cancer. Aimed to elucidate whether antioxidants could be a reality in the management of breast cancer patients, this review focuses on the latest investigations regarding the ambivalent ro

SUBMITTER: Grinan-Lison C 

PROVIDER: S-EPMC7911462 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature